We have been doing some fascinating and cutting edge anti-infective work.  Not only are we conducting our standard workhorse models, such as Mouse Protection Test and Neutropenic Thigh, but we have been developing some customized and sophisticated infection models.

Suture Infection in Rats.  We developed and conducted a number of studies evaluating dermal staph infections associated with different sorts of unique suture technology.  The histologic section shows the deep dermal suture abscess in an untreated lesion.

Infected suture abscess

Bacterial Endocarditis in Rabbits. We optimized and conducted a number of studies evaluating  test articles in  a model of vegetative valvular endocarditis with  staph infection in rabbits.  We  use a guided imaging method to place the intracardiac catheter.

Ocular Keratitis and Conjunctivitis in Rabbits. We optimized and conducted a number of studies evaluating treatment regimes in bacterial and viral infection of the damaged cornea and conjunctiva in rabbits.  In addition to creating the corneal lesion, we used sophisticated imaging of the cornea and anterior segment.

Contact us for more information on our infection modeling.