Osteogenesis imperfecta model in mice
CBI is now offering an established model of Ostegenesis imperfecta in OIM mutant mice. In the model, mice develop with fragile bones with spontaneous fractures. In an OI study, mice are assessed… Read More
Bone Histology
I would like to let our clients know about our validated bone capabilities. We offer decalcified and nondecalcified bone preparation, as well as grinding, GMA and MMA. We can provide a variety… Read More
Animal Welfare in the Biomedical Research Environment
Many people in the dog and horse animal world that I interact with love their animals and want the best for them medically. At the same time, they think that they want… Read More
CBI offers fluorescent in situ hybridization
The histology department at CBI offers FISH (fluorescence in situ hybridization) as an important tool in preclinical research and toxicology. FISH is a cytogenetic technique employed to detect and localize the presence or absence of specific intracellular DNA sequences onchromosomes.… Read More
MiniPigs for Toxicology and Preclinical Research
Mini pigs are becoming increasingly more popular as nonrodent species for toxicology and for a wide variety of pharmacology modeling. They are especially useful for burn and wound healing, dermatology, ocular, dental,… Read More
FDA Site Visit to CBI
We just had a very successful site visit to CBI by the FDA! They spent a week with us and we had NO GLP findings! One area that the FDA appears to… Read More
CIRM and VIACYTE, INC PRESS RELEASE
CBI congratulates our friends and colleagues at VIACYTE, INC on their FDA success. CBI is the industry leader in conducting difficult and complicated IND enabling and research studies with Stem Cells… Read More
Human Tumor Bank
Our histology laboratory now boasts a wide variety of human tumors for multiple uses related histology, immunohistochemistry, marker characterization, RNA Isolation and laser capture. These include tumors of: ovarian, lung, muscle, breast,… Read More
Melanin associated antigen induced uveitis
CBI offers a lovely MAA ocular inflammation model in rats that recapitulates the human disease of Anterior Uveitis. We spent several years developing the antigen and then validating and optimizing the inflammation.… Read More
Perilymph collection for otic pharmacokinetics
Pharmaceuticals used for otic indication or that may have otic toxicity such as chemotherapy agents or aminoglycocides may accumulate in the peri-lymph which accumulates in the cochlea. The volume of the cochlea… Read More
