Blog – Comparative Biosciences, Inc.
  • CBI Home

Toxicologic and Histopathologic Peer Review

By Carol Meschter • August 28, 2017 • Uncategorized

Histopathologic Peer Review (PR) is an important tool in aiding quality and accuracy in the histopathologic assessment of toxicology studies. The peer review verifies and improves the accuracy and quality of pathology diagnoses and interpretations. Pathology peer review is recommended when important risk assessment or business decisions are based on nonclinical studies.  PR is important in large scale studies such as 1-year studies and carcinogenicity studies and in particular when there is significant human safety at stake or if a company making far reaching business decisions about a product; it is particularly important where carcinogenicity is a potential issue.  It is a highly structured collaborative process and provides an independent, but highly expert, review of a designated subset of slides and the Study Pathologist’s microscopic diagnosis. The Study Pathologist and the PR pathologist work collaboratively to come to a consensus on the findings, if there are differences of opinion.

 

The contemporaneous Peer Review is performed by an experienced ACVP board-certified pathologist often with special expertise around the salient features of the study in consideration.  The review includes assessment of a designated subset of slides as indicated by the OECD guidelines and the recommendations of the STP.   It generally occurs before the pathology study is signed and the peer reviewed provides a certificate attesting to consensus.  The certificate includes the list of tissues evaluated, data reviewed, and a signed declaration of consensus.  The statement may be retained in the data or the in the final toxicology report.

 

Comparative Biosciences, Inc offers experienced Peer Review.  We have a GLP validated pathology data acquisition system suitable for Peer Review, an experienced ACVP pathologist, a comprehensive document control system and a full time Quality Assurance Unit.

 

 

References: 

The Society of Toxicologic Pathologists (2010) Recommendations for Pathology
Peer Review Toxicologic Pathology Online first publication October 5, 2010

Morton D, Sellers RS, Barale-Thomas, E, et al:  Recommendations for Pathology Peer Review. Toxicologic Pathology, 38: 1118-1127, 2010

OECD Series on Principles of Good Laboratory Practice and Compliance
Monitoring: No, 16, Advisory Document of the Working Group on Good Laboratory
Practice-Guidance on the GLP Requirements for Peer Review of Histopathology,
OEeD Publishing, Paris, Dec 2014.

The Society of Toxicologic Pathologists (2015) Review of the Organization for
Economic Co-operation and Development (OECD) Guidance on the GLP
Requirements for Peer Review of Histopathology. Toxicologic Pathology Online
first publication 24-Jul-2015, pp 1-8.

 

Tweet
76
The (Non)Reproducibility Crisis, Part 4
Scleroderma: Tight Skin Mouse Model at CBI

About the Author

Carol Meschter

You Might Also Like

  • New Blog.mr

  • Red Duroc Swine for Dermal Studies

  • NIH blocks Chimera Research

  • ELISAs at CBI

76 Comments

  • Log in to Reply cbd site August 25, 2021 at 2:48 pm

    … [Trackback]

    […] Read More to that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply ซ่อมรถบรรทุก September 7, 2021 at 10:07 pm

    … [Trackback]

    […] Read More here on that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply purchase nembutal online September 18, 2021 at 4:33 pm

    … [Trackback]

    […] Find More to that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply Glo Carts October 10, 2021 at 2:56 pm

    … [Trackback]

    […] Information to that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply dewaqq online November 8, 2021 at 9:28 am

    … [Trackback]

    […] Info to that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply credit card dumps 2016 November 13, 2021 at 2:45 am

    … [Trackback]

    […] Here you can find 13403 additional Info on that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply sbo November 18, 2021 at 3:55 pm

    … [Trackback]

    […] Information to that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply blogsvirals November 25, 2021 at 8:51 am

    … [Trackback]

    […] Find More Information here to that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply Ford Transit Custom Sport Double Cab November 26, 2021 at 3:55 pm

    … [Trackback]

    […] Find More on on that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply best stomach fat burner December 3, 2021 at 11:15 pm

    … [Trackback]

    […] Here you will find 69430 more Information to that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply friends bet sex games December 7, 2021 at 11:00 am

    hentai flash games sex https://cybersexgames.net/

  • Log in to Reply http://144.91.94.11/elangqq/ December 10, 2021 at 4:39 am

    … [Trackback]

    […] Read More on that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply bettilt giris December 10, 2021 at 10:58 am

    … [Trackback]

    […] Find More on that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply highest payout online casino December 10, 2021 at 2:07 pm

    casino gambling online https://casinoonlinek.com/

  • Log in to Reply best us online casino December 11, 2021 at 3:05 am

    bet mgm online casino pa https://onlinecasinoad.com/

  • Log in to Reply golden eagle casino online December 12, 2021 at 12:13 pm

    online casino florida https://casinogamesmachines.com/

  • Log in to Reply hallmark online casino December 12, 2021 at 3:58 pm

    real vegas online casino https://conline-casinos-hub.com/

  • Log in to Reply สล็อตเว็บตรง December 12, 2021 at 5:29 pm

    … [Trackback]

    […] Information to that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply foxwoods online casino December 13, 2021 at 4:49 am

    ocean online casino app https://onlinecasinos4me.com/

  • Log in to Reply golden nugget online casino promotions December 13, 2021 at 7:09 am

    mychoice online casino https://online2casino.com/

  • Log in to Reply ceasars casino online December 13, 2021 at 2:18 pm

    raging bull casino online slots https://casinoonlinet.com/

  • Log in to Reply free bonus without deposit online casino December 13, 2021 at 3:50 pm

    foxwoods online casino https://casinosonlinex.com/

  • Log in to Reply keto shrimp scampi December 14, 2021 at 7:08 am

    keto snacks https://ketogenicdiets.net/

  • Log in to Reply diet doctor keto December 14, 2021 at 9:47 am

    keto lunch recipes https://ketogendiet.net/

  • Log in to Reply keto bagel recipe December 15, 2021 at 4:48 am

    keto vegetarian recipes https://ketogenicdietinfo.com/

  • Log in to Reply keto desserts recipe December 15, 2021 at 7:53 am

    keto carb limit https://ketogendiets.com/

  • Log in to Reply college essay writing help December 15, 2021 at 2:18 pm

    writing the essay nyu https://anenglishessay.com/

  • Log in to Reply what to write in a college essay December 15, 2021 at 7:53 pm

    the best essay writing services https://topessayswriter.com/

  • Log in to Reply write an analytical essay December 16, 2021 at 12:28 pm

    help writing college essay https://yoursuperessay.com/

  • Log in to Reply pay essay writing December 17, 2021 at 12:15 am

    essay writing website https://howtowriteessaytips.com/

  • Log in to Reply write a persuasive essay December 17, 2021 at 3:04 am

    persuasive writing essays https://checkyouressay.com/

  • Log in to Reply orange county gay trans dating December 17, 2021 at 7:05 am

    what is gay dating like at uvu? https://gayprideusa.com/

  • Log in to Reply older gay dating sites December 17, 2021 at 9:02 am

    gay man dating ftm https://gayfade.com/

  • Log in to Reply free gay dating services December 17, 2021 at 11:24 am

    gay leather dating https://gaysugardaddydatingsites.com/

  • Log in to Reply kardinal stick December 18, 2021 at 4:39 pm

    … [Trackback]

    […] Find More here on that Topic: compbio.com/our-blog/toxicologic-histopathologic-peer-review/ […]

  • Log in to Reply guide to critical thinking December 19, 2021 at 8:06 am

    critical thinking social work https://criticalthinkingbasics.com/

  • Log in to Reply critical thinking problem solving December 19, 2021 at 9:55 am

    critical thinking examples https://criticalthinkinginstitute.com/

  • Log in to Reply types of critical thinking December 19, 2021 at 11:04 am

    nursing critical thinking development https://criticalthinking2020.net/

  • Log in to Reply critical thinking and problem solving December 19, 2021 at 1:35 pm

    define critical thinking in psychology https://uncriticalthinking.com/

  • Log in to Reply reflection essay December 19, 2021 at 2:17 pm

    how to write conclusion of essay https://choosevpn.net/

  • Log in to Reply how to start a narrative essay December 19, 2021 at 5:06 pm

    philosophy of education essay https://topvpndeals.net/

  • Log in to Reply apply texas essay prompts 2021 December 19, 2021 at 7:37 pm

    summary essay example https://tjvpn.net/

  • Log in to Reply college essay example December 19, 2021 at 9:37 pm

    states synonym for essay https://thebestvpnpro.com/

  • Log in to Reply process analysis essay examples December 19, 2021 at 11:48 pm

    how to write a 5 paragraph essay https://vpn4home.com/

  • Log in to Reply how to start an argumentative essay examples December 20, 2021 at 12:31 am

    thesis example for essay https://vpnshroud.com/

  • Log in to Reply free essay checker December 20, 2021 at 3:37 am

    uc college essay prompts https://vpnsrank.com/

  • Log in to Reply how to write a 5 paragraph essay December 20, 2021 at 5:58 am

    essay topics for college https://vpn4torrents.com/

  • Log in to Reply high school application essay examples December 20, 2021 at 6:26 am

    what is an informative essay https://windowsvpns.com/

  • Log in to Reply 3knitting December 31, 2021 at 3:29 am

    3winsome

  • Log in to Reply christian gay dating app for android January 2, 2022 at 5:00 am

    gay autism dating vancouver washington https://gaypridee.com

  • Log in to Reply is plenty of fish a gay dating site? January 2, 2022 at 5:58 am

    gay foot fetish dating https://gay-buddies.com

  • Log in to Reply dating dominant gay men January 2, 2022 at 7:00 am

    black gay dating https://gayprideusa.com

  • Log in to Reply senior gay women dating January 2, 2022 at 8:00 am

    gay dating aps https://speedgaydate.com

  • Log in to Reply gay muscle dating January 2, 2022 at 10:01 am

    white gay liberal dating interracial to avoid being seen as racist https://gaysugardaddydatingsites.com

  • Log in to Reply gay chat rooms ring central January 14, 2022 at 3:43 am

    zoom cam rooms gay chat https://bjsgaychatroom.info/

  • Log in to Reply free chat lines bie and gay January 14, 2022 at 8:56 am

    gay webcam chat sites https://gaytgpost.com/

  • Log in to Reply gay phone chat lines January 14, 2022 at 12:43 pm

    gay chat room finding sex https://gay-buddies.com/

  • Log in to Reply slots of vegas January 28, 2022 at 10:55 am

    free netbet slots https://2-free-slots.com/

  • Log in to Reply free slots that pay cash January 28, 2022 at 1:10 pm

    pearl warriors slots https://freeonlneslotmachine.com/

  • Log in to Reply vegas wotld slots January 28, 2022 at 6:20 pm

    better off ed slots https://candylandslotmachine.com/

  • Log in to Reply free slots 777 three rows January 28, 2022 at 9:37 pm

    all free slots https://pennyslotmachines.org/

  • Log in to Reply gsn casino free slots January 28, 2022 at 11:06 pm

    free slots games online https://slotmachinesworld.com/

  • Log in to Reply mobile deluxe slots February 3, 2022 at 8:08 am

    slots blaze casino https://slotmachinesforum.net/

  • Log in to Reply real money slots online February 3, 2022 at 1:26 pm

    calendar with time slots https://slot-machine-sale.com/

  • Log in to Reply ali baba slots game free February 3, 2022 at 5:36 pm

    free slots on facebook https://beat-slot-machines.com/

  • Log in to Reply las vegas world free slots February 3, 2022 at 7:24 pm

    hollywood slots https://download-slot-machines.com/

  • Log in to Reply best time to play slots February 4, 2022 at 12:00 am

    best online slots https://411slotmachine.com/

  • Log in to Reply free quarter diamond slots February 4, 2022 at 3:59 am

    little green men slots https://www-slotmachines.com/

  • Log in to Reply baba wild slots casino February 4, 2022 at 6:26 am

    quick hit slots free https://slotmachinegameinfo.com/

  • Log in to Reply help with my dissertation February 10, 2022 at 9:28 am

    help with dissertation https://buydissertationhelp.com/

  • Log in to Reply best dissertation writing service February 11, 2022 at 7:30 am

    dissertation writing tutor https://dissertationwriting-service.com/

  • Log in to Reply buy dissertation help February 11, 2022 at 10:09 am

    best dissertation writing services uk https://help-with-dissertations.com/

  • Log in to Reply i need help writing my dissertation February 11, 2022 at 4:36 pm

    dissertation help management https://mydissertationwritinghelp.com/

  • Log in to Reply doctoral dissertation help usa February 11, 2022 at 7:24 pm

    sample dissertation https://dissertations-writing.org/

  • Log in to Reply dissertation writing services reviews February 11, 2022 at 8:51 pm

    dissertation custom writing https://helpon-doctoral-dissertations.net/

  • Log in to Reply 1yearling June 18, 2022 at 10:46 am

    3sensory

Leave a Reply

You must be logged in to post a comment.

MEET CAROL MESCHTER

MEET CAROL MESCHTER
Carol Meschter, DVM, PhD, DACVP is a founder of Comparative Biosciences, Inc. She is an experienced board-certified veterinary pathologist with expertise in toxicology and animal models. She has over 100 publications and is a reviewer for several major journals. She is a scientific editorial reviewer for Toxicologic Pathology, Veterinary Pathology, AVMA Journal, AJVR, J Applied Immunology, and has over 100 publications.

Recent Posts

  • Intraocular Lens Implantation Preclinical Models at CBI
  • Histopathology on Human Muscle Biopsies from patients affected with a Glycogen Storage Disease
  • Models of Pulmonary Infection
  • Cannabis Preclinical Pharmacology and Toxicology
  • CBI Sponsors Ototoxicity and ABRs in Toxicologic Assessments at the ACT
Twitter Linkedin
Blog – Comparative Biosciences, Inc.

Comparative Biosciences, Inc. • Phone: 408.738.9260 Copyright © 2017 Comparative Biosciences, Inc. All rights reserved. Website/Blog designed by Rollinson Advertising Design.