Veterinary Preclinical Studies

Comparative Biosciences Inc., a premier veterinary preclinical contract research organization, is committed to providing expert high-quality contract research services to the veterinary and animal health industry. Extensive experience industry provides our staff with a solid track record in preclinical veterinary research and drug development capabilities. We work closely with both sponsors and Veterinary Clinical Research horseOrganizations to support studies that are needed to support regulatory submissions to the USDA and FDA. We offer toxicology, pharmacokinetic and pharmacology studies in all relevant veterinary species (juvenile and adult) such as dogs, cats, minipigs, pigs, and also mice, rats, hamsters, guinea pigs, chinchillas, ferrets, gerbils, and rabbits, limited studies with small ruminants and horses are also possible. We offer a wide range of routes of administration as well as unusual and specialized routes of administration for a wide variety of test articles including small molecules, large molecules, biologics (vaccines, antibodies, proteins, toxins, viral, stem cells, radiolabeled products), and other related test articles and devices.


Beginning with early assessment of new molecules including single dose, multiple dose, and targeted studies, as well as directed or investigative toxicology, and finishing with complete FDA or USDA enabling toxicology programs, CBI provides expertise, attention, and care on every study. Our study directors are experienced, communicative, and attentive, and we produce high-quality GLP reports in a very timely fashion.


CBI offers a complete range of research services in the area of pharmacokinetic, toxicokinetic, bioequivalence, bioavailability, and ADME studies in normal and in disease states.

Pharmacology and Efficacy

CBI provides a range of pharmacology capabilities across a spectrum of indications that ensure reliable results in the drug-discovery-development process for companion animals and farm animals. Assessment and analysis modalities are fine-tuned to meet the specific requirements demanded in each targeted area of scientific investigation. Our specialties in Veterinary Pharmacology include:

  • Anti-infectives
  • Arthritis
  • Anthelmintics
  • Arthropods
  • Bioequivalence
  • Bone and joint orthopedics
  • Cardiovascular
  • Cancer chemotherapy
  • Dermal allergy and atopy
  • Devices and implants
  • Flea allergy dermatitis
  • Inflammation
  • Livestock & Companion Animal Diseases
  • Neonatal and juvenile
  • Neurologic
  • Ocular
  • Pain
  • Parasites
  • Pulmonary
  • Reproductive
  • Surgical modeling
  • Wound healing
  • Vaccines
  • Special Problems: Our scientists will develop any model needed to address special problems in preclinical development


CBI offers histology and pathology, incuding immunohistochemistry, plastics, devices and histomorphometry in both a GLP and nonGLP environment for studies generated within CBI as well as from animals from field and academic studies. We welcome tissues from both companion animals and large farm or exotic animals.

MI with contraction bands
Micrograph showing contraction band necrosis, a histopathologic finding of myocardial infarction (heart attack)
Equine synovitis at 40x magnification
Equine synovitis at 20x magnification