Dermal Immune Mediated Disease

                  Imiquimod-Induced Psoriasis Psoriasis is a chronic skin condition associated with multiple contributing factors including autoimmune disease. The imiquimod-induced Psoriasis model is particularly translational into the clinic as it has many of the significant markers of human disease, including histopathology of lesions and strong activation of the […]

Dermal Immune Mediated Disease

A Model of Psoriasis Psoriasis is a chronic skin condition associated with multiple contributing factors including autoimmune disease. The imiquimod-induced Psoriasis model is particularly translational into the clinic as it has many of the significant markers of human disease, including histopathology of lesions and strong activation of the immune system. CBI’s extensive immunology expertise allows […]

Oncolytic Viral Vaccine

Oncolytic Viral Vaccine Toxicology at CBI   Introduction to Toxicology. “Oncolytic viral therapy is a new promising strategy against cancer. Oncolytic viruses (OVs) can replicate in cancer cells but not in normal cells, leading to lysis of the tumor mass.” Background. Oncolytic viral vaccines represents a novel and exciting approach to the treatment of cancer. In 2015, […]

Intraocular Lens Implantation

            Surgical Procedure: ↑ Lens phakoemulsion to remove lens, insertion of “Intraocular Lens Implantation” and final appearance of successfully implanted IOL.   Intraocular Lens Implantation Preclinical Models at CBI An intraocular lens implant is a synthetic, artificial lens placed inside the eye that replaces the focusing power of a natural lens […]

Pompe?

          Cannabis Pharmacology. Cannabis Pharmacology. Assessment of Cannabis Products for Purity, Effectiveness and Safety. Now that medical cannabis has achieved some degree of legality and public acceptability, Cannabis Products are becoming a serious industry, particularly in California. Comparative Biosciences Inc. offers an initial package of purity, efficacy and safety assessments on […]

Pompe Disease

        Pompe Disease Pompe’s Disease or Glycogen Storage Disease II, is a rare, inherited fatal disease affecting infants. It is an autosomal recessive metabolic disorder which damages muscle and nerve cells throughout the body due to an accumulation of glycogen in the lysosome resulting from a deficiency of the lysosomal acid alpha-glucosidase […]

Fibrosis and Inflammation

<div class=”container”> <a href=”https://www.compbio.com/wp-content/uploads/2018/02/broncho_D.png”><img class=”alignleft size-full wp-image-3742″ src=”https://www.compbio.com/wp-content/uploads/2018/02/broncho_D.png” alt=””/></a> <div class=”centered”>CBI Congratulates <br>Meridigen Biotech Co. Ltd<br>on their successful IND submission<br>for their project:<br><br> UMC119-01 (hUC-MSCs)<br>for the treatment of<br>Bronchopulmonary Dysplasia. <br> <br> <a href=”https://www.compbio.com/wp-content/uploads/2018/02/cbi-Bronchopulmonary.Dysplasia.pdf” class=”button”>VIEW NOW</a> <img alt=”” src=”https://www.compbio.com/wp-content/uploads/2018/02/redline.png”> </div> </div>

CBI Published Article

          CBI-In Vivo Efficacy Study Showing Comparative Advantage of Bacterial Infection Prevention with Zip-type Skin Closure Device vs. Subcuticular Sutures   “In Vivo Efficacy Study Showing Comparative Advantage of Bacterial Infection Prevention with Zip-type Skin Closure Device vs. Subcuticular Sutures.” Recently CBI conducted a study for Zipline Medical, Inc. in which […]

HELLO WORLD

           Low and high magnification of multifocal chronic pneumonitis with hyperplastic bronchial lymphoid tissues throughout lungs of mice.   Model of Murine Hypersensitivity Pneumonitis (Farmer’s Lung) Farmer’s Lung is a hypersensitivity pneumonitis induced by the inhalation of biologic dusts coming from hay dust or mold spores or any other agricultural products. It results in a type III hypersensitivity inflammatory response  and can progress […]

Model of Nasal Aspergillosis in Rabbits

          Left: Low magnification photomicrograph demonstrating conidia in a fungal granuloma in the sinus of a rabbit (PAS)                                                    Right: High magnification of photomicrograph demonstrating conidia in […]