CBI offers a wide variety of toxicology and pharmacokinetic studies to support both early discovery and development phase compounds.
- Toxicology Capabilities
- Special Toxicology Capabilities
- Pharmacokinetic Capabilities
Toxicology Capabilities
- Acute, subacute, and chronic toxicity studies
- Oral, ocular, dermal, intra-tracheal, IV, IM, SC, IP, joint fluid, short-infusion and other routes of administration including intracranial by stereotaxic injection or infusion
- Hematology and Clinical Chemistry
- Clinical pathology research services are available in either a research or GLP environment on a wide variety of laboratory animal species.
- Small molecules, proteins, antibodies, viral vectors
- Rapid turn-around time
- GLP and Non-GLP
- Data collection and assessment using validated LABCAT Data Aquisition Program
Special Toxicology Capabilities for Unusual or Investigational Toxicology Issues
- Quick, inexpensive mini-tox studies (compound sparing for rapid assessment of new molecules in rodents)
- Ocular, dermal, short infusion, intracerebral, intrathecal, and other routes
- Surgical toxicity studies
- Hypothesis-directed or investigative studies
- Small molecules, proteins, antibodies
- Radionuclide studies
Pharmacokinetic CapabilitiesRapid-Screening Toxicology and Pharmacokinetic Studies
- Quick mini-PK studies (compound sparing for rapid assessment of new molecules in rodents)
- Routine single or multiple dose pharmacokinetic studies
- Oral, ocular, dermal, intra-tracheal, IV, IM, SC, IP, short-infusion and other routes
- Small molecules, proteins, antibodies
- Radionuclide studies
- More information on pharmacokinetic capabilities
Toxicology and Pharmacokinetic Studies Include
- Experienced, highly trained study directors
- Senior staff with extensive experience in drug discovery and development
- Complete and comprehensive documentation
- High quality, rapid reports
- All pathology performed by board-certified pathologists
- All clinical chemistry reviewed and interpreted by board-certified pathologists
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