toxicity studiesHematology and Clinical Chemistry

CBI offers a wide variety of toxicology and pharmacokinetic studies to support both early discovery and development phase compounds.

Toxicology Capabilities
Special Toxicology Capabilities
Pharmacokinetic Capabilities

Toxicology Capabilities

  • Acute, subacute, and chronic toxicity studies
  • Oral, ocular, dermal, intra-tracheal, IV, IM, SC, IP, joint fluid, short-infusion and other routes of administration including intracranial by stereotaxic injection or infusion
  • Hematology and Clinical Chemistry
  • Clinical pathology research services are available in either a research or GLP environment on a wide variety of laboratory animal species.
  • Small molecules, proteins, antibodies, viral vectors
  • Rapid turn-around time
  • GLP and Non-GLP
  • Data collection and assessment using validated LABCAT Data Aquisition Program

Special Toxicology Capabilities for Unusual or Investigational Toxicology Issues

  • Quick, inexpensive “mini-tox” studies (compound sparing for rapid assessment of new molecules in rodents)
  • Ocular, dermal, short infusion, intracerebral, intrathecal, and other routes
  • Surgical toxicity studies
  • Hypothesis-directed or investigative studies
  • Small molecules, proteins, antibodies
  • Radionuclide studies

Pharmacokinetic Capabilities—Rapid-Screening Toxicology and Pharmacokinetic Studies

  • Quick “mini-PK” studies (compound sparing for rapid assessment of new molecules in rodents)
  • Routine single or multiple dose pharmacokinetic studies
  • Oral, ocular, dermal, intra-tracheal, IV, IM, SC, IP, short-infusion and other routes
  • Small molecules, proteins, antibodies
  • Radionuclide studies
  • More information on pharmacokinetic capabilities

Toxicology and Pharmacokinetic Studies Include

  • Experienced, highly trained study directors
  • Senior staff with extensive experience in drug discovery and development
  • Complete and comprehensive documentation
  • High quality, rapid reports
  • All pathology performed by board-certified pathologists
  • All clinical chemistry reviewed and interpreted by board-certified pathologists

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