Preclinical Ophthalmology

Preclinical ophthalmology studies are key to selecting early compounds or chemical structures for further assessment as well as assessing candidates for advancement into Clinical testing. Assessment and analysis modalities are fine-tuned to meet the specific requirements demanded in each targeted area of ophthalmologic investigation.

Our team has demonstrated unique and extensive expertise in preclinical contract ophthalmology studies and is committed and dedicated to providing a complete range of ophthalmology services.

Methods of Assessment

  • Clinical Signs
  • Body weights
  • Draize scoring
  • McDonald-Shadduck scoring
  • IOP
  • Pachymetry
  • Ultrasound
  • Ocular photography
  • Tonovet Schirmer Test
  • Phenol red thread test
  • Tear Break up test
  • Bengal rose thread test
  • Slit Lamp Biomicroscopy
  • Fundoscopy
  • Phoenix retinal scanner
  • ERG
  • OCT
  • Angiography
  • Fluorescein dye corneal examination
  • Aqueous or Vitreal Protein
  • Aqueous or vitreal cell count
  • Full range of species

Ophthalmology Services

  • Exploratory/proof-of-concept studies
  • Good Laboratory Practice (GLP) toxicology studies
  • Histopathology/immunohistochemistry assays
  • In vivo¬†models
  • Pharmacology studies
  • Pharmacokinetics studies