Accelerate the development of your new dermatology drug, biologic or device with our dermatological study services. Our team has unique and extensive expertise in all phases of the drug development process for preclinical contract dermatology studies for small and large molecules, irritants, carcinogens and dermal devices.

A vital role is played by our own natural biomolecules in the healing process, including their contribution to the growth of new cells and the development of new blood vessels that provide nutrients to those cells. Here at Comparative Biosciences, Inc. we are developing the models to test the therapeutics that could accelerate the wound healing process.

Your studies can be conducted in any species. Our team has more than 10 years’ experience selecting optimal models for dermatologic toxicology, efficacy, pharmacokinetics and pharmacology studies.

We have validated efficacy models in:

  • Dermal burns
  • Incision/excision surgical wounds
  • Abrasion wound models
  • Thermal or UV burns
  • Atopic dermatits
  • Acne models in Rhino mice
  • Psoriasis models
  • Inflammation models

Methods of Assessment

  • Dermal optical coherence tomography (OCT)
  • Enzyme-linked immunosorbent assays (ELIZA)
  • Immunohistochemistry assays
  • Histology from our in-house histopathology lab
  • Laser Doppler for blood flow
  • Silhouette photography

Dermatology Services

  • Exploratory/proof-of-concept studies
  • GLP toxicology studies
  • Histopathology/immunohistochemistry assays
  • In vivo animal models
  • Pharmacology studies
  • Pharmacokinetics studies