Discovery toxicology is a key process in the identification, characterization and selection of new products for development. CBI offers a number of fast, cost-effective research programs designed to assess, characterize and rank new molecules for toxicity and efficacy and to assist in the selection process.

For early discovery toxicology projects, CBI also offers a range of non-GLP exploratory toxicity studies for early assessment of molecules including single dose, multiple dose and targeted studies, as well as directed or investigative toxicology.

ROUTES OF ADMINISTRATION

  • Standard routes
  • Intravesicular
  • Intravaginal
  • Intrarectal
  • Intranasal
  • Intradermal
  • Ocular
  • Aural-otic
  • Buccal
  • Patches
  • Devices
  • Device-drug combination
  • Infusion
  • Dermal
  • Topical
  • Wounds
  • Sublingual
  • Nanoparticles
  • Device stem cell combination
  • Intrathecal
  • Intracerebral
  • Intratumoral
  • Intracardiac
  • Intra-intestinal
  • Others upon request

TYPES OF TOXICOLOGY STUDIES

Acute Studies

  • Acute
  • Dose ranging
  • Limit dosing
  • Maximum tolerated dose
  • Single dose

Subacute & Subchronic

  • 1-week subacute
  • 2-week subacute
  • 4-week subchronic
  • 8-week subchronic

Chronic & Carcinogenicity

  • 3-month chronic
  • 6-month chronic
  • 9-month chronic
  • 1-year carcinogenicity
  • 2-year carcinogenicity

Special or custom toxicology

  • 1-year chronic
  • 2-year chronic
  • Stem cells
  • Surgical toxicity
  • Transgenic carcinogenicity
  • Others upon request