Atopic Dermatitis Model at CBI
CBI offers a robust validated murine model of atopic dermatitis characterized by edema, perivascular eosinophil and monocyte inflammation, and increased epidermal thickness in taped stripped skin that has been repeatedly sensitized with… Read More
CBI Exhibits at ARVO
CBI exhibited at the ARVO meeting in Seattle this past week. It was an excellent, well attended meeting, with strong scientific presentations and posters. Our sales managers, Douglas Crowder and Eric Altman… Read More
Hyperoxygenation-induced pulmonary fibrosis in infant rat pups
Exposure of neonatal infant rats to 2 weeks of hyperoxygenation followed by return to room air leads to pulmonary alveolar wall fibrosis, enlargement of the alveolar space and inflammation. This is analogous… Read More
Bone models at CBI
We are currently conducting some interesting bone models. One model investigates the osteogenic effects of various scaffolds and stem cell preparations on calvarial defects in rats. A second model investigates the role… Read More
Unusual routes of administration
CBI offers pharmacology and GLP toxicology studies with unusual routes of administration: 1. Ocular 2. Otic 3. Intra-tracheal 4. Hyper or hypo oxygenation (ocular and pulmonary lesions) 5. Stem cells 6. Dermal… Read More
Red Duroc Swine for Dermal Studies
Red Duroc swine are a frequent choice for preclinical studies, including scarring, wound healing and burns. CBI is offering preclinical studies using these unique and interesting animals.… Read More
NIH blocks Chimera Research
The NIH has recently blocked Chimera research and funding at major university centers. This appears to be driven by anti-science factions and animal rights groups who seem to be envisioning scenes from… Read More
ELISAs at CBI
We are now offering ELISAs at CBI. The enzyme-linked immunosorbent assay (ELISA) is a common laboratory technique which is used to measure the concentration of an analyte (ex. cytokines, antibodies, antigens, other… Read More
New Preclinical and Toxicologic Imaging Capabilities at CBI
We are offering a number of new imaging capabilities to support toxicology and preclinical studies. There will be an eblast coming out shortly and an update on our webpage. These capabilities include… Read More
OCT assessment of bleomycin-induced dermal fibrosis
Here at CBI, we are using OCT to track the development and treatment of bleomycin-induced dermal fibrosis. The OCT has proved to be highly accurate and sensitive, able to reliably assess small… Read More
