CBI is proud to announce that we have developed and validated a Laser-Induced Choroidal Neovascularization Model in Rabbits. The development of this model is the result of nearly 2 years of investigation and experimentation. In this model, we place 10-15 lesions in the retina using a unique lasering process developed by CBI. The lesions form consistently and are composed of a fibrovascular plaque containing new small capillaries typical of neovascularization. Rabbits are examined funduscopically and histopathologically. Lesions are assessed histomorphometrically for area and volume of lesion size. Treatment is reflective of the individual study protocol.
Below on the left is a fundus photograph of lesions at 2 weeks. On the right is a correlative Subretinal neovascular plaque typical of the lesion. For more information, contact Mike Zamora at mike.zamora@compbio.com, 408 306 8464.
