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Incumbent will be the lead pathologist and head of the Pathology/Histology service group at CBI. Will be regarded as a senior scientist amongst our team of researchers and scientists. As an investigational veterinary pathologist, the incumbent will be integral to development or refinement of new or existing in vivo pharmacology models of disease. Incumbent will also conduct standard toxicological pathology assessments. A strong professional presence is expected when interacting with customers and partners and the incumbent is expected to exercise a high level of professionalism and independence.
Essential Duties and Responsibilities
- Develop, validate, and implement both established and innovative pharmacology models of disease.
- Support inquiries from business development personnel regarding pharmacology models and engage in client information exchanges / TCs regarding new or existing models.
- Represent the Company to clients and other stakeholders effectively and diplomatically, with due regard for client service.
- Perform microscopic evaluation and interpretation of tissues. Provide scientific consultation and interpretation of macroscopic or microscopic lesions.
- Build and supervise team ensuring they are well trained and performing efficiency. Ensure SOP and GLP compliance (as applicable) for pathology and histology operations.
- Recruit and hire qualified personnel for approved positions within areas of responsibility.
- Formulate policies, author SOPs and supervise activities in area of responsibility to ensure productivity, quality and safety in operations.
- Utilize good documentation skills including protocol and report preparation.
- Author comprehensive pathology narrative reports of macroscopic and microscopic findings. Act as a hands-on Principal Investigator for pathology portions of internal and external studies.
- Communicate the significance of pathologic findings to study directors, clients and other individuals.
- Together with senior management, develop annual plans for areas of responsibility, including equipment and staffing needs.
- Interact cooperatively and effectively with Study Directors, clients, consultants, and other technical staff.
- Support compliance with all applicable laws and regulations; support AAALAC accreditation.
- Act as clinical veterinarian when needed.
Knowledge, Skills and Experience
Degree in veterinary medicine or equivalent and Diplomat ACVP credential are required. Minimum of 3 years relevant experience past Diplomat ACVP boards. Written and verbal communication skills appropriate for a professional environment and that support client interactions. Able to work in a fast-paced matrix environment. Moderate proficiency with Microsoft Office products including Word and Excel.
Expertise in toxicologic pathology. Experience and interest in designing and optimizing animal models of human disease is required. Experience is desired in microscopic evaluation and application of knowledge of underlying disease processes to both in vivo pharmacology models and GLP toxicology studies.
Comparative Biosciences is seeking to recruit a Research Associate. The ideal candidate will possess the technical expertise to function effectively in a good laboratory practice (GLP) toxicology and drug development environment, supporting study directors by implementing and coordinating biomedical research and development studies and meeting study specific timelines.
The right candidate needs to possess good problem-solving skills, a good understanding of study techniques and excellent planning and communication skills. The position may be filled at either the research associate I or II level depending on qualifications and experience of the candidate.
Primary responsibilities will include:
- Dosing models
- Observing and recording baseline and experimental findings in models
- Preparing for and performing minor surgical procedures with supervision
- Necropsy of research models
- Understanding and complying with standard operating procedures, GLPs and other applicable regulations
- Some animal husbandry, as needed
- Certification by AALAS as a laboratory animal technician (LAT) or laboratory animal technologist (LATg) or higher within the first 12 months of employment
- Up to five years’ experience working in a pharmaceutical, biotech or contract research organization, preferably in preclinical development
- Basic knowledge of handling of research models in a biomedical research and development environment
- Familiarity with Microsoft Word and Excel
- BS degree in a biological sciences field
- Three or more years of experience conducting in-life pharmacology, pharmacokinetic, surgical and/or toxicology studies and performing necropsies and data collection in GLP and non-GLP environments
Comparative Biosciences, Inc. is seeking to recruit a Study Director for in vivo pharmacology and toxicology studies. The ideal candidate will possess the technical expertise and scientific acumen to function effectively in a GLP laboratory with a primary mission to support drug discovery and development. This position involves experimental design and interpretation as well as oversight and conduct of laboratory bench work.
Opening is immediate. Position is full-time.
The successful candidate will be expected to work both independently and as part of a highly
collaborative group. The candidate will join a dynamic, multi-disciplinary team of scientists in drug development, playing a key role in establishing in vivo efficacy models and conducting toxicology as well as pharmacokinetic studies. Must be able to use these models to evaluate new drug candidates.
• Design, develop, characterize, implement and validate relevant in vivo pharmacology / efficacy models for the evaluation of drug candidates.
• Design, document, analyze / interpret studies addressing the safety assessment of pre-clinical/clinical drug candidates.
• Communicate effectively and interact productively with clients and other visiting scientists and stakeholders in the studies conducted.
• Prepare high-quality study protocols and reports as well as manage and interpret data.
• Work collaboratively and positively influence multi-disciplinary teams.
Required Experience, Education and Skills:
• PhD. in the area of Biology, Pharmacology or Toxicology. DVM with experience in subject areas of research.
• Demonstrated expertise in in vivo pharmacology and/or toxicology.
o Minimum 2-5 years of direct experience with in vivo pharmacology or efficacy models in an industry setting, or;
o Minimum 3 years of experience working in Pharmaceutical, Biotech or Contract Research Organization.
• Strong scientific writing skills, excellent communication and organizational skills, critical problem-solving abilities, and a commitment to excellence.
• Proficiency in data analysis and use of standard software tools.
• Excellent interpersonal skills with emphasis on communication and relationship building.
• Experience in working closely with Research Associates and other technical staff.
• Must be able to read and write effectively in English with a professional style.
• Flexible and able to manage multiple simultaneous projects.
• Experience with GLP study conduct is desirable but not required.
Maintenance of animal care procedures. Tasks such as feeding of animals and treatment of animals, and cleaning and maintenance of the Animal Research Facility in compliance with SOP’s and GLP’s.
Essential Duties and Responsibilities
• Animal husbandry, including daily clinical observations, for mice, rats, rabbits and other species as needed.
• May assist in some procedures as needed.
• Preparation for studies, including setting up and breaking down procedure and surgical rooms, and preparing instruments, equipment, and supplies.
• Maintaining accurate records such as room maintenance sheets and daily observation forms.
• Understanding and complying with SOP’s, GLP’s and other applicable regulations.
• Performing any other tasks directed by supervisor, required by the facility, or as qualified by training and experience.
• Working in an efficient and timely manner with minimal supervision.
Knowledge, Skills and Experience
High School Diploma or equivalent preferred. Must be able to read and write in English. Able to work in a fast paced matrix environment. Must be goal oriented and highly self-motivated.
• Activities may require standing for extended periods?
• Able to carry and lift up to 50 pounds
Work is predominantly performed on company site.
Comparative Biosciences, Inc. is committed to maintaining diversity in our workplace. Comparative Biosciences, Inc. is an Equal Opportunity Employer.
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